Induction of insulin resistance by the adipokines resistin, leptin, PAI-1 and RBP4 in human megakaryocytes
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منابع مشابه
Chenodeoxycholic acid, an endogenous FXR ligand alters adipokines and reverses insulin resistance.
Adipose tissue secretes adipokines that regulate insulin sensitivity in adipocytes and other peripheral tissues critical to glucose metabolism. Insulin resistance is associated with severe alterations in adipokines characterized by release of increased pro-inflammatory cytokines and decreased anti-inflammatory cytokines from adipose tissue. The role of Farnesoid X receptor (FXR) activation on a...
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BACKGROUND Retinol-binding protein-4 (RBP4) is a novel adipokine able to modulate the action of insulin in several tissues. A variable degree of insulin resistance characterizes the vast majority of hypertensive (HYP) patients. The aim of this study was to evaluate the relationship between RBP4 and essential hypertension, exploring potential links between RBP4 and other adipokines with some pro...
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Objective The main purpose of the current study was to investigate the association between QTc and various insulin sensitive or insulin resistant adipocytokines such as leptin, adiponectin, RBP4, and PAI-1 as well as inflammatory markers, oxidative stress and endothelial function in patients with type 2 diabetes. Method QTc, blood and urine tests were performed in 101 type 2 diabetic patients h...
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